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Home - Products - Endocrinology/Hormones - 5-HT Receptor - 8-Hydroxy-DPAT hydrobromide

8-Hydroxy-DPAT hydrobromide

CAS No. 76135-31-4

8-Hydroxy-DPAT hydrobromide ( 8-OH-DPAT hydrobromide )

Catalog No. M27597 CAS No. 76135-31-4

8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide) is a potent and selective 5-HT1A agonist with a pIC50 of 8.19. 8-Hydroxy-DPAT hydrobromide has a selectivity of almost 1000 fold for a subtype of the 5-HT1 binding site.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    8-Hydroxy-DPAT hydrobromide
  • Note
    Research use only, not for human use.
  • Brief Description
    8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide) is a potent and selective 5-HT1A agonist with a pIC50 of 8.19. 8-Hydroxy-DPAT hydrobromide has a selectivity of almost 1000 fold for a subtype of the 5-HT1 binding site.
  • Description
    8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide) is a potent and selective 5-HT1A agonist with a pIC50 of 8.19. 8-Hydroxy-DPAT hydrobromide has a selectivity of almost 1000 fold for a subtype of the 5-HT1 binding site.
  • Synonyms
    8-OH-DPAT hydrobromide
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    PARP1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    76135-31-4
  • Formula Weight
    328.3
  • Molecular Formula
    C16H25NO·HBr
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    OC1=C2C[C@H](CCC2=CC=C1)N(CCC)CCC.Br
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Almahli H, Hadchity E, Jaballah MY, Daher R, Ghabbour HA, Kabil MM, Al-Shakliah NS, Eldehna WM. Development of novel synthesized phthalazinone-based PARP-1 inhibitors with apoptosis inducing mechanism in lung cancer. Bioorg Chem. 2018 Apr;77:443-456.
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